WebSymbol: Celf5: Name: CUGBP, Elav-like family member 5: RGD ID: 1565016: Description: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site select WebApr 1, 2024 · RRM3_CELF3_4_5_6; RNA recognition motif 2 in CUGBP Elav-like family member CELF-3, CELF-4, CELF-5, CELF-6 and similar proteins cl26386 Location: 214 …
National Center for Biotechnology Information - CELF2
WebFunctional assays showed that miR-20a promotes proliferation and invasion and inhibits apoptosis in glioma cells. The bioinformatic analysis showed that CELF2 (CUGBP Elav-like family member 2) is a direct target gene of miR-20a, which was confirmed using a luciferase reporter assay. The demonstration that hCUGBP1 is involved in the control of mRNA deadenylation and instability like xCUGBP1 came next. In mammalian cell extract as well as in xenopus egg extracts, depletion and rescue experiments showed that specific binding of CUGBP1 to the 3'UTR of mRNA is required for the targeted … See more CUG triplet repeat, RNA binding protein 1, also known as CUGBP1, is a protein which in humans is encoded by the CUGBP1 gene. See more Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM … See more • Human CELF1 genome location and CELF1 gene details page in the UCSC Genome Browser. See more It is estimated that 5 to 8% of human mRNAs are unstable because of mRNA instability elements in their 3' untranslated regions (3'UTR). A number of such elements have … See more • Timchenko LT, Timchenko NA, Caskey CT, Roberts R (1996). "Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy" See more ph navy uniform
UniProt
WebNX_O95319 - CELF2 - CUGBP Elav-like family member 2 - Function. RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative … WebNX_O95319 - CELF2 - CUGBP Elav-like family member 2 - Portals. RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative … WebENCODES a protein that exhibits long noncoding RNA binding (ortholog); mRNA 3'-UTR binding (ortholog); pre-mRNA binding (ortholog); INVOLVED IN mRNA splice site selection (ortholog); posttranscriptional gene silencing (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hypoparathyroidism-deafness-renal disease syndrome … phn bag content