High affinity copper uptake protein
WebLOC100178573 high affinity copper uptake protein 1-like [ (vase tunicate)] Gene ID: 100178573, updated on 26-Oct-2024. Summary Other designations. high affinity ... Web30 de dez. de 2005 · High affinity copper binding by wild type PrP has been confirmed by the independent techniques indicating the presence of specific tight copper binding sites …
High affinity copper uptake protein
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WebBecause copper uptake at the cell membrane is a crucial step in copper acquisition, yeast genes encoding the high affinity copper transport proteins are tightly regulated in response to copper levels to ensure that … Web16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper …
Web21 de mar. de 2024 · High Affinity Copper Uptake Protein 1 3 4 Copper Transporter 1 3 4 Solute Carrier Family 31 (Copper Transporters), Member 1 3 Copper Transport 1 Homolog 3 External Ids for SLC31A1 Gene HGNC: 11016 NCBI Entrez Gene: 1317 Ensembl: ENSG00000136868 OMIM®: 603085 UniProtKB/Swiss-Prot: O15431 Previous HGNC … WebIt was shown that a gene, CTR1, encoded a multispanning plasma membrane protein that was specifically required for high affinity copper transport into yeast.The CTR1 gene product is a protein composed of 406 amino acid residues. A second high affinity copper uptake protein, encoded by the CTR3 gene, was subsequently identified. The two gene …
Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... WebThe redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. However, little is known …
WebThese high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights into how cells acquire and regulate this essential nutrient. The … fmc ft. worthWebalthough the role of Ctr1 internalization in copper uptake is currently unclear. Furthermore, exposure of yeast cells to high copper concentrations ($10 mM) triggers the degradation of Ctr1 at the plasma membrane in a mechanism that is inde-pendent of endocytosis and vacuolar proteases (14). The Ctr1 and Ctr3 high affinity copper transport ... greensboro nc sign regulationsWeb11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and transformed this mutant allele [COPT1(M44A)] into S. cerevisiae ctr1Δctr3Δ strain which lacks high affinity copper transporters CTR1 and CTR3 and cannot grow on … fmc fort washington mdWeb1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... greensboro nc shuttlesWeb5 de abr. de 2024 · Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with … fmc fund managementWebHigh affinity copper uptake protein 1 Alternative names Copper transporter 1 ( rCTR1) Liver regeneration-related protein LRRGT00200 Solute carrier family 31 member 1 … fmc frisco dialysisWebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … fmcf vic
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