Human bcma uniprot

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August undefined, 2024

WebAnti-BCMA Antibody is a highly specific rabbit polyclonal antibody, that targets B-cell Maturation Protein & has been tested in western blotting, IHC & Immunofluorescence. Anti-BCMA Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA WebUniprot ID: Q02223. Description: Recombinant human BCMA protein with C-terminal human Fc and 6×His tag. Expression Host: HEK293. Delivery: In Stock. Molecular …

Anti-BCMA Antibody ABC840 - EMD Millipore

Web5 Feb 2024 · B-cell maturation antigen (BCMA), a cell surface receptor recognizing B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL), play an important role in the survival of long-lived PCs in the bone marrow ( 14–17 ). BCMA is expressed on PCs and is highly expressed on myeloma cells while being absent on most other cells ( 18 ). WebThe BCMA / NF-κB - HEK293 recombinant cell line has been transfected with full-length human BCMA cDNA (Genbank #NM_001192) under control of a CMV promoter for high … april banbury wikipedia

BCMA / NF-κB – Reporter HEK293 Recombinant Cell Line - BPS …

Web17 Jun 2016 · The second pulse with human anti-BCMA antibody reveals increased BCMA staining that is reduced by cycloheximide by ~25%. It therefore appears that about 25% of the BCMA receptor re-expression … WebFully biologically active when compared to standard. The ED 50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less … Web14 Apr 2024 · Abstract. Background: The introduction of novel targeted therapies and immunotherapies has dramatically improved responses and overall survival in multiple myeloma (MM) patients. However, greater than 50% MM achieve refractory or relapse (r/r) within five-year due to MM target heterogeneity and bone marrow tumor … april berapa hari

Human BCMA Protein, His Tag - DIMA Biotechnology

Recombinant Human BCMA protein (ab139210) Abcam

WebChimeric antigen receptor (CAR) T cell immunotherapy for multiple myeloma (MM) is currently becoming standard of care in advanced MM. 1 2 Most approaches currently focus on targeting B cell maturation antigen (BCMA) as a single target because BCMA is critical for maintaining tumor cell phenotypes and expression is limited to the B and plasma cell … WebRecombinant Human BCMA/TNFRSF17 Protein (His Tag) Uniprot : Q02223 Cat.No.: PKSH033486 Expression host: P.Pichia Filter: Manual MSDS Recombinant Human BCMA / TNFRSF17 / CD269 Protein (C-His)-Elabscience To Purchase PKSH033486 Size: Price: $92 Qty: Welcome to order from local distributors. FAQs for Recombinant Proteins Have … april calendar drawingsWebRecombinant Human BCMA protein (Tagged) (Biotin) (ab269984) Datasheet SDS Submit a review Submit a question $675 Product size 50 µg Add to basket Order now and get it on … april baker bell youtube

"WebBCMA, B cell maturation antigen, is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one … " - Human bcma uniprot

Human bcma uniprot

WebHomo sapiens (Human) Synonyms: BCM, BCMA. Uniprot: Q02223 go to UniProt. Biological function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK go to UniProt. WebSpecificity This antibody recognizes human BCMA (B Cell Maturation Protein). BCMA is a receptor for BAFF and April, two novel members of the TNF superfamily of proteins …

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Web11 Aug 2009 · Having observed that Xenopus Fn14 cross-reacts with human TWEAK, despite its relatively low sequence homology to human Fn14, we examined the … WebThe wild-type sequence of APRIL is available at UNIPROT/075888 and is show below (SEQ ID No. 1). It is not a classical secreted protein in that it has no signal peptide. ... Four different myeloma samples were stained with the rat anti-human BCMA mAb Vicky1. The results are shown in FIG. 7. In clinically and morphologically typical myelomas ...

Web27 May 2024 · In this issue of Blood, Wang et al report their phase 1 trial of CT103, a fully human 4-1BBζ chimeric antigen receptor (CAR) targeting the B-cell maturation antigen (BCMA), in 18 patients with relapsed or refractory multiple myeloma (MM). 1 WebELISA Human TNFRSF17 ELISA Kit (BCMA) (ab213840) Primary Anti-BCMA antibody [EPR22457-260] (ab253242) Protein Native Human IgG2 protein (ab90284) View more …

Web1 Sep 2024 · Among the potential targets for CAR cell therapy against MM, B-cell maturation antigen (BCMA) represents an ideal one due to its restrictive expression pattern in B-cell lineage cells and... WebRecombinant clonal stable CHO cell line constitutively expressing full length human BCMA protein, also known as TNFRSF17, (Genbank #NM_001192). Surface expression of …

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WebHuman Antibody Type Monoclonal Host Species Mouse Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) Preparation The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. Concentration april bank holiday 2023 ukWebUS20240060847A1 US17/898,208 US202417898208A US2024060847A1 US 20240060847 A1 US20240060847 A1 US 20240060847A1 US 202417898208 A US202417898208 A US 202417898208A US 2024060847 A1 US2024060847 A1 US 2024060847A1 Authority US United States Prior art keywords heavy chain antibody bcma sequence seq Prior art … april biasi fbWeb21 Apr 2015 · J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) ... Gene … april chungdahmWebRecombinant Human BCMA protein (ab139210) Recombinant Protein Recombinant Human BCMA protein (ab50089) Related Products Anti-BCMA antibody - C-terminal (ab5972) … april becker wikipediaWebFully biologically active when compared to standard. The ED 50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less … april awareness days ukWebTumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. april bamburyWebPE anti-human ROR1 Antibody - ROR1, also known as NTRKR1, is a type I transmembrane protein and member of the ROR subfamily of surface receptors. ... UniProt View … april bank holidays 2022 uk