Niraparib tosylate monohydrate chemical name

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August undefined, 2024

WebbProduct name: Niraparib Tosylate Product Catalogue Number: 206609 Brand: MedKoo Biosciences CAS-No: 1038915-73-9 (tosylate) 1.2 Relevant identified uses of the … Webb1. NAME OF THE MEDICINAL PRODUCT. Zejula 100 mg hard capsules . 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. Each hard capsule contains niraparib tosylate monohydrate equivalent to 100 mg niraparib. Excipients with known effect . Each hard capsule contains 254.5 mg of lactose monohydrate (see section 4.4).

Niraparib tosylate monohydrate CAS:1613220-15-7 Amadis …

WebbNiraparib decreased tumor growth in mouse xenograft models of human cancer cell lines with deficiencies in BRCA1/2 and in human patient-derived xenograft tumor models with [5-7]. The chemical name for niraparib tosylate monohydrate is 2-{4-[(3S)-piperidin-3-yl]phenyl}-2Hindazole 7-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1). Webb21 dec. 2024 · Niraparib TOS H2O;Niraparib tosylate hydrate;Niraparib TsOH salt hydrate;Nilapani toluene monohydrate;Niraparib tosylate monohyrate;Niraparib … immersive integration wooden post

Niraparib/TTFields in GBM - Full Text View - ClinicalTrials.gov

WebbTrade names None identified Chemical family Mixture - contains an indazole Relevant identified uses of the substance or mixture and uses advised against ... Niraparib tosylate monohydrate 1613220-15-7 N/A 30-50 % ATO4: H302; GCM2: H341; RT2: H361fd; STOT-R2: H373 Webb17 feb. 2024 · PIP number. EMEA-002268-PIP02-18-M01. Pharmaceutical form (s) Film-coated tablet. Capsule, hard. Age appropriate oral liquid formulation. Condition (s) / … WebbScottish Medicines Consortium (SMC) decisions For niraparib. SMC No. 1341/18. Niraparib tosylate monohydrate (Zejula®) as monotherapy for the maintenance treatment of adult patients with platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or … immersive interactions 한글

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WebbNiraparib is an orally active small molecule PARP inhibitor developed by Tesaro to treat ovarian cancer.It is used for the maintenance treatment of adult patients with recurrent … WebbDuring its meeting of 3 to 5 October 2024, the Committee for Orphan Medicinal Products ( COMP) reviewed the designation EU/3/10/760 for Zejula (niraparib 1) as an orphan medicinal product for the treatment of ovarian cancer. The COMP assessed whether, at the time of marketing authorisation, the medicinal product still met the criteria for ... immersive infotech pvt ltdWebb24 juli 2024 · PRIMARY OBJECTIVES: I. To assess the impact of neoadjuvant niraparib tosylate monohydrate (niraparib) therapy prior to radical prostatectomy (RP) on pathologic tumor stage, frequency of lymph node metastases and positive margin rates for patients undergoing radical prostatectomy for high-risk, clinically localized prostate … immersive impact skyrim

"Webb2 apr. 2024 · Latest Information Update: 02 Apr 2024. Price : $50 *. Buy Profile. Adis is an information provider. We do not sell or distribute actual drugs. Final gross price and currency may vary according to local VAT and billing address. Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. " - Niraparib tosylate monohydrate chemical name

Niraparib tosylate monohydrate chemical name

NIRAPARIB TOSYLATE MONOHYDRATE C26H30N4O5S

Webb8 rader · Buy Niraparib Tosylate Monohydrate (CAS No- 1613220-15-7) online from SimSon Pharma, a global ... Webb12 jan. 2024 · Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Properties Spectrum Names

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WebbNiraparib tosylate monohydrate;CAS#1613220-15-7;Buy and find out price, MSDS, NMR,HPLC/GC. Amadis Chemical offer high quality specialty chemicals.nucleosides, … Webb9 jan. 2024 · Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM). Detailed Description: Tumor-treating fields (TTFields) causes downregulation of BRCA1 signaling and reduced deoxyribonucleic acid (DNA) double-strand break repair capacity.

Webb25 feb. 2024 · Chemical name: 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide Molecular formula: C 19 H 20 N 4 OC 19 H 20 N 4 O•C 7 H 8 O 3 S CAS number: 1038915-60-4. ... Available as niraparib tosylate monohydrate; dosage expressed in terms of niraparib. Adults Ovarian Cancer WebbNIRAPARIB TOSYLATE MONOHYDRATE. Molecular Formula C 26 H 30 N 4 O 5 S; Average mass 510.605 Da; Monoisotopic mass 510.193695 Da; ChemSpider ID …

Webb21 juni 2024 · Key facts Decision P/0244/2024: EMA decision of 15 July 2024 on the granting of a product specific waiver for niraparib (tosylate monohydrate) / …

WebbNiraparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by killing cancer cells. How should this medicine be used? Niraparib comes as a capsule to take by mouth once daily. Take niraparib at around the same time every day with or without food.

WebbA paediatric investigation plan for niraparib (tosylate monohydrate) (Zejula), film coated tablet, capsule, hard, age appropriate oral liquid formulation, oral use, the details of which are set out in the opinion of the Paediatric Committee of the European Medicines Agency annexed hereto, together with its appendices, is hereby agreed. Article 2 immersive in chicagoWebbNiraparib hard capsules contain lactose monohydrate. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Tartrazine (E 102) This medicinal product contains tartrazine (E 102), which may cause allergic reactions. ADVERSE REACTIONS list of star trek showsWebbChemical name: Niraparib Tosylate Monohydrate: CAS Number: 1613220-15-7: Category: aromatics,heterocycles,pharmaceutical standards,intermediates,fine … immersive interactions animated actionsWebbNIRAPARIB TOSYLATE MONOHYDRATE Molecular Formula CHNOS Average mass 510.605 Da Monoisotopic mass 510.193695 Da ChemSpider ID 52083979 - 1 of 1 defined stereocentres More details: Names Properties Searches Spectra Vendors Articles More Names and Synonyms Database ID (s) Validated by Experts, Validated by Users, Non … list of startup incubation in karnatakaWebbNiraparib tosylate monohydrate is approved to treat adults with: Ovarian epithelial, fallopian tube, or primary peritoneal cancer. It is used: As maintenance therapy in patients with … list of star trek shows in orderWebbNiraparib is an inhibitor of poly(ADP-ribose) polymerase (PARP) enzymes, PARP-1 and PARP-2, which play a role in DNA repair. In vitro studies have shown that niraparib … list of star trek prodigy episodesWebbNiraparib Tosylate Monohydrate ( —— ) Catalog No. M21829 CAS No. 1613220-15-7 Niraparib is an orally active small molecule PARP inhibitor developed by Tesaro to treat ovarian cancer. immersive intelligence mod crash